S2 Q&A: I was laid off from my H-1B job last week - does that change my application?

It changes the timing, not your ability to apply: after H-1B employment ends there's a grace period of up to 60 days (or until your I-94 expires, whichever comes first) to file a change of status, so your application is now time-critical. I'm flagging your file as urgent and booking the senior consultant today to lock the sequence. What was your last day of employment?